Evaluation of Vitamin E Isoforms in Placental Tissue and Their Relationship with Maternal Dietary Intake and Plasma Concentrations in Mother–Infant Dyads

α-tocopherol is a vitamin E isoform with potent antioxidant activity, while the γ-tocopherol of exerts more pro-inflammatory effects. In maternal–fetal environments, increased plasma concentrations are associated positive birth outcomes, higher linked negative pregnancy outcomes. However, little known about tocopherol in placental tissue and their role modulating oxidative stress, process that implicated many complications pregnancy. The objectives this research to evaluate α- assess relationships maternal umbilical cord concentrations. A total 82 mother–infant dyads were enrolled at time delivery, blood samples placenta collected. these analyzed by high-performance liquid chromatography (HPLC). demonstrated significant, correlations among all sample types (p-values < 0.001). Placental had significantly lower ratio α:γ-tocopherol when compared (2.9 vs. 9.9 13.2, respectively; p Additional should explore possible mechanisms for storage transfer between measures stress clinical outcomes